Thalamo-cortical Relationship in Evoked Cortical Responses Following Human Ventrolateral Thalamic Stimulation

Responses of primary somatosensory cortical neurons to controlled mechanical stimulation.

The results of psychophysical studies suggest that displacement velocity may contribute significantly to the sensation of subcortical somatosensory neurons. The cortical correlates of these phenomena, however, are not known. In the present study the responses of rapidly adapting (RA) neurons in the forelimb region of cat primary somatosensory cortex (SI) to controlled displacement of skin and h...

Cortical projection of the thalamic ventrolateral nuclear group in monkeys.

The ventrolateral nuclear group of the dorsal thalamus in the monkey consists of the large cell mass lying between the external and internal medullary laminae rostral to the pulvinar. Fibers from these nuclei terminate on a sector occupying the middle portion of the dorsolateral cerebral cortex. Previous investigators using, in most instances, the method of retrograde degeneration, have determi...

Evoked Multisensory Cortical Representations During Unisensory Stimulation

Cortical responses evoked by laser speckle.

Human cortical evoked responses elicited by patterns are very size and focus dependent, but those produced by moving laser speckle patterns (LASCERs) remain similar in amplitude and subjective sharpness over a wide (+/- 20 D) variation in added lens power. Moreover, cortical signal amplitudes evoked by speckle displays with high average spatial frequencies are significantly larger than those re...

Thalamo–cortical network underlying deep brain stimulation of centromedian thalamic nuclei in intractable epilepsy: a multimodal imaging analysis

OBJECTIVE Deep brain stimulation (DBS) of the centromedian thalamic nucleus (CM) can be an alternative treatment option for intractable epilepsy patients. Since CM may be involved in widespread cortico-subcortical networks, identification of the cortical sub-networks specific to the target stimuli may provide further understanding on the underlying mechanisms of CM DBS. Several brain structures...